Email: info@neweastbio.com   |  Call: 6109452007

HDAC2 Rabbit pAb

Anti-HDAC2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225269

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225269
Product Name:   Anti-HDAC2 Rabbit pAb
Synonyms:   HDAC2; Histone deacetylase 2; HD2
UNIPROT ID:   Q92769
Background:    In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.
Immunogen:    Peptide sequence around aa. 392~396 (E-D-S-G-D) derived from Human HDAC2.
Applications:    WB,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 55 kDa; Observed MW: 60 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of HDAC2 in Hela using HDAC2 (Ab394) antibody.

Western blot analysis of HDAC2 in 293, 3T3 and COS7 lysates using HDAC2 (Ab394) antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using HDAC2 (Ab394) antibody (left) or the same antibody preincubated with blocking peptide (right).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications