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HINT2 Rabbit pAb

Anti-HINT2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216552

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216552
Product Name:   Anti-HINT2 Rabbit Polyclonal Antibody
Synonyms:   HIT-17
UNIPROT ID:   Q9BX68 (Gene Accession – BC047737 )
Background:    Hint2 (histidine triad nucleotide binding protein 2), also known as HIT-17, is a 163 amino acid secreted protein that contains one HIT domain, a histidine triad that has catalytic activity toward the †-phosphate of ribonucleotides. Via its HIT domain, Hint2 is thought to function as a hydrolase that is encoded by a gene which maps to chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Immunogen:    Fusion protein of human HINT2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 216552(HINT2 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 216552(Anti-HINT2 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216552(Anti-HINT2 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D220742(Anti-HINT2 Antibody) at dilution 1/50.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart tissue, human hepatocellular carcinoma tissue;
Primary antibody: 216552(HINT2 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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