NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S217106 | ||||
Product Name: Anti-HIPK4 Rabbit Polyclonal Antibody | ||||
Synonyms: | ||||
UNIPROT ID: Q8NE63 (Gene Accession – BC034501 ) | ||||
Background: HIPK4 (Homeodomain-interacting protein kinase 4) is a 616 amino acid protein that localizes to the cytoplasm and exists as two isoforms that are produced by alternative splicing events. Like other members of the HIPK family, HIPK4 functions as a protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to act as a corepressor of target transcription factors. | ||||
Immunogen: Fusion protein of human HIPK4 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 50-200; ELISA: 1000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse, Rat | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling, Cancer | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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