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Histone H1.8 Rabbit pAb

Anti-Histone H1.8 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225481

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225481
Product Name:   Anti-Histone H1.8 Rabbit pAb
Synonyms:   H1.8; H1oo; osH1
UNIPROT ID:   Q8IZA3
Background:    May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling .
Immunogen:    The antiserum was produced against synthesized peptide derived from human Histone H1. AA range:131-180
Applications:    IHC-P,IHC-F,ICC/IF,ELISA
Recommended Dilutions:    IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:   
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of Histone H1.8 in HeLa cells using Histone H1.8 antibody. Sample with blocking peptide on the right.
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