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HMGA1 Rabbit pAb

Anti-HMGA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213596

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213596
Product Name:   Anti-HMGA1 Rabbit Polyclonal Antibody
Synonyms:   HMG-R, HMGIY, HMGA1A
UNIPROT ID:   P17096 (Gene Accession – NP_665906 )
Background:    This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human HMGA1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 213596(HMGA1 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 213596(Anti-HMGA1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 213596(Anti-HMGA1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D160486(Anti-HMGA1 Antibody) at dilution 1/30.
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