Email: info@neweastbio.com   |  Call: 6109452007

HMGB1 Rabbit mAb

Anti-HMGB1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261656

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261656
Product Name:   Anti-HMGB1 Rabbit Monoclonal Antibody
Synonyms:   HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
UNIPROT ID:   P09429
Background:    High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.
Immunogen:    A synthetic peptide of human HMGB1
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-2D8
MW:    Calculated MW: 25 kDa; Observed MW: 25 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using HMGB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of HMGB1 in K562, rat Brain, C6, 3T3, Hela lysates using HMGB1 antibody.
          Publications