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HNF1A Rabbit pAb

Anti-HNF1A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220007

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220007
Product Name:   Anti-HNF1A Rabbit Polyclonal Antibody
Synonyms:   HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20
UNIPROT ID:   P20823 (Gene Accession – NP_000536 )
Background:    The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5′-GTTAATNATTAAC-3′. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen:    Synthetic peptide of human HNF1A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 220007(HNF1A Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 220007(Anti-HNF1A Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 220007(Anti-HNF1A Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D260769(Anti-HNF1A Antibody) at dilution 1/50.
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