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HOXC5 Rabbit pAb

Anti-HOXC5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215971

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215971
Product Name:   Anti-HOXC5 Rabbit Polyclonal Antibody
Synonyms:   CP11; HOX3; HOX3D
UNIPROT ID:   Q00444 (Gene Accession – NP_061826 )
Background:    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC5, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5′ non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants have been described for HOXC5. The transcript variant which includes the shared exon apparently doesn’t encode a protein. The protein-coding transcript variant contains gene-specific exons only.
Immunogen:    Synthetic peptide of human HOXC5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 215971(HOXC5 Antibody) at a dilution of 1/55(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 215971(Anti-HOXC5 Antibody) at dilution 1/55.
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