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HSD11B2 Rabbit pAb

Anti-HSD11B2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220611

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220611
Product Name:   Anti-HSD11B2 Rabbit Polyclonal Antibody
Synonyms:   AME; AME1; HSD2; HSD11K; SDR9C3
UNIPROT ID:   P80365 (Gene Accession – NP_000187 )
Background:    There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity.
Immunogen:    Synthetic peptide of human HSD11B2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular, Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220611(HSD11B2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220611(Anti-HSD11B2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 220611(Anti-HSD11B2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D261764(Anti-HSD11B2 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human normal kidney tissue;
Primary antibody: 220611(HSD11B2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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