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HSD3B2 Rabbit pAb

Anti-HSD3B2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217522

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217522
Product Name:   Anti-HSD3B2 Rabbit Polyclonal Antibody
Synonyms:   HSDB; HSD3B; SDR11E2
UNIPROT ID:   P26439 (Gene Accession – BC038419 )
Background:    The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Immunogen:    Fusion protein of human HSD3B2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 217522(HSD3B2 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 217522(Anti-HSD3B2 Antibody) at dilution 1/50.
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