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HTR3A Rabbit pAb

Anti-HTR3A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216312

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216312
Product Name:   Anti-HTR3A Rabbit Polyclonal Antibody
Synonyms:   HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
UNIPROT ID:   P46098 (Gene Accession – BC002354 )
Background:    The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen:    Fusion protein of human HTR3A
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 40-200;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 216312(HTR3A Antibody) at a dilution of 1/60(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 216312(Anti-HTR3A Antibody) at dilution 1/60.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: TM4 cell lysate;
Primary antibody: 216312(HTR3A Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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