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IFT57 Rabbit pAb

Anti-IFT57 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219118

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219118
Product Name:   Anti-IFT57 Rabbit Polyclonal Antibody
Synonyms:   HIPPI; MHS4R2; ESRRBL1
UNIPROT ID:   Q9NWB7 (Gene Accession – BC011899 )
Background:    Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Immunogen:    Fusion protein of human IFT57
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 219118(IFT57 Antibody) at a dilution of 1/85(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 219118(Anti-IFT57 Antibody) at dilution 1/85.
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