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IGF1 Receptor Rabbit mAb

Anti-IGF1 Receptor Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263378

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263378
Product Name:   Anti-IGF1 Receptor Rabbit Monoclonal Antibody
Synonyms:   IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
UNIPROT ID:   P08069
Background:    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Immunogen:    Recombinant protein of human IGF1 Receptor
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-3C8
MW:    Calculated MW: 155 kDa; Observed MW: 95 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IGF1 Receptor in Hela, A549, MCF-7, U251 lysates using IGF1 Receptor antibody.
          Publications