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IL-17 Receptor C Rabbit pAb

Anti-IL-17 Receptor C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225452

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225452
Product Name:   Anti-IL-17 Receptor C Rabbit pAb
Synonyms:   IL17RC; Interleukin-17 receptor C; IL-17 receptor C; IL-17RC; Interleukin-17 receptor homolog; IL17Rhom; Interleukin-17 receptor-like protein; IL-17RL; ZcytoR14
UNIPROT ID:   Q8NAC3
Background:    This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
Immunogen:    The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770
Applications:    WB,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 86 kDa; Observed MW: 70 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IL-17 Receptor C in RAW264.7 lysates using IL-17RC antibody.

Western blot analysis of IL-17 Receptor C in various lysates using IL-17 Receptor C antibody.

Western blot analysis of IL-17 Receptor C in HuvEc lysates using IL-17RC antibody.
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