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IL10RA Rabbit pAb

Anti-IL10RA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216297

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216297
Product Name:   Anti-IL10RA Rabbit Polyclonal Antibody
Synonyms:   CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1
UNIPROT ID:   Q13651 (Gene Accession – BC028082 )
Background:    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Immunogen:    Fusion protein of human IL10RA
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tosil tissue using 216297(IL10RA Antibody) at a dilution of 1/60(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tosil tissue is first treated with the fusion protein and then with 216297(Anti-IL10RA Antibody) at dilution 1/60.
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