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IL12A Rabbit pAb

Anti-IL12A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221126

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221126
Product Name:   Anti-IL12A Rabbit Polyclonal Antibody
Synonyms:   P35; CLMF; NFSK; NKSF1; IL-12A
UNIPROT ID:   P29459 (Gene Accession – NP_000873 )
Background:    This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Immunogen:    Synthetic peptide of human IL12A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221126(IL12A Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221126(Anti-IL12A Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 221126(Anti-IL12A Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D262509(Anti-IL12A Antibody) at dilution 1/20.
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