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IL17RC Rabbit pAb

Anti-IL17RC Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216301

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216301
Product Name:   Anti-IL17RC Rabbit Polyclonal Antibody
Synonyms:   CANDF9; IL17RL; IL17-RL
UNIPROT ID:   Q8NAC3 (Gene Accession – BC006411 )
Background:    This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
Immunogen:    Fusion protein of human IL17RC
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 216301(IL17RC Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 216301(Anti-IL17RC Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216301(Anti-IL17RC Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220168(Anti-IL17RC Antibody) at dilution 1/55.
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