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IL18BP Rabbit pAb

Anti-IL18BP Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216304

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216304
Product Name:   Anti-IL18BP Rabbit Polyclonal Antibody
Synonyms:   IL18BPa
UNIPROT ID:   O95998 (Gene Accession – BC044215 )
Background:    The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen:    Fusion protein of human IL18BP
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 216304(IL18BP Antibody) at a dilution of 1/65(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 216304(Anti-IL18BP Antibody) at dilution 1/65.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: MCF-7 cell lysate;
Primary antibody: 216304(IL18BP Antibody) at dilution 1/900;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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