NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N225007 | ||||||
Product Name: Anti-Integrin alpha 4 Rabbit pAb | ||||||
Synonyms: ITGA4; CD49D; Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD49d | ||||||
UNIPROT ID: P13612 | ||||||
Background: ITGA4 Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. | ||||||
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ITGA4. AA range:571-620 | ||||||
Applications: WB,IHC-P,ELISA | ||||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Clone ID: – | ||||||
MW: Calculated MW: 115 kDa; Observed MW: 120 kDa | ||||||
Isotype: IgG | ||||||
Purification: Affinity Purified | ||||||
Species Reactivity: Human,Mouse,Rat | ||||||
Conjugation: Unconjugated | ||||||
Modification: Unmodified | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||||
Research Areas: Signal Transduction | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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