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Integrin beta 3 Rabbit pAb

Anti-Integrin beta 3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225477

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225477
Product Name:   Anti-Integrin beta 3 Rabbit pAb
Synonyms:   ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
UNIPROT ID:   P05106
Background:    Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).
Immunogen:    The antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGB3. AA range:621-670
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 87 kDa; Observed MW: 87 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Integrin beta 3 in NIH3T3 lysates using Integrin beta3 antibody.

Western blot analysis of Integrin beta 3 in 3T3 lysates using Integrin beta 3 antibody.
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