NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S220633 | ||||||
Product Name: Anti-IPO9 Rabbit Polyclonal Antibody | ||||||
Synonyms: Imp9 | ||||||
UNIPROT ID: Q96P70 (Gene Accession – NP_060555 ) | ||||||
Background: Importin-9, also known as Imp9 or IPO9, is a 1,041 amino acid protein that contains one importin N-terminal domain and belongs to the Importin-? family. Localized to both the nucleus and the cytoplasm, Importin-9 functions as a nuclear transport receptor that mediates the docking of the Importin complex to the nuclear pore complex (NPC). Importin-9 mediates nuclear import of H2B histone, Ribosomal Protein S7 and Ribosomal Protein L18A. The gene encoding Importin-9 is located on human chromosome 1, the largest human chromosome that spans about 260 million base pairs and makes up 8% of the human genome. | ||||||
Immunogen: Synthetic peptide of human IPO9 | ||||||
Applications: ELISA, WB, IHC | ||||||
Recommended Dilutions: IHC: 50-200;WB: 200-1000;ELISA: 1000-2000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Isotype: Immunogen-specific rabbit IgG | ||||||
Purification: Antigen affinity purification | ||||||
Species Reactivity: Human, Mouse | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling, Cancer | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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