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IPO9 Rabbit pAb

Anti-IPO9 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220633

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220633
Product Name:   Anti-IPO9 Rabbit Polyclonal Antibody
Synonyms:   Imp9
UNIPROT ID:   Q96P70 (Gene Accession – NP_060555 )
Background:    Importin-9, also known as Imp9 or IPO9, is a 1,041 amino acid protein that contains one importin N-terminal domain and belongs to the Importin-? family. Localized to both the nucleus and the cytoplasm, Importin-9 functions as a nuclear transport receptor that mediates the docking of the Importin complex to the nuclear pore complex (NPC). Importin-9 mediates nuclear import of H2B histone, Ribosomal Protein S7 and Ribosomal Protein L18A. The gene encoding Importin-9 is located on human chromosome 1, the largest human chromosome that spans about 260 million base pairs and makes up 8% of the human genome.
Immunogen:    Synthetic peptide of human IPO9
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220633(IPO9 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220633(Anti-IPO9 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220633(Anti-IPO9 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D261793(Anti-IPO9 Antibody) at dilution 1/20.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human fetal brain tissue, Hela cells;
Primary antibody: 220633(IPO9 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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