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IRF1 Rabbit pAb

Anti-IRF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213613

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213613
Product Name:   Anti-IRF1 Rabbit Polyclonal Antibody
Synonyms:   MAR, IRF-1
UNIPROT ID:   P10914 (Gene Accession – NP_002189 )
Background:    IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Immunogen:    Synthetic peptide of human IRF1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 213613(IRF1 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 213613(Anti-IRF1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 213613(Anti-IRF1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D160520(Anti-IRF1 Antibody) at dilution 1/40.

Gel: 12%SDS-PAGE, Lysate: 30 μg;
Lane 1-2: NIH/3T3 cells, Jurkat cells;
Primary antibody: 213613(IRF1 Antibody) at dilution 1/750;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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