Email: info@neweastbio.com   |  Call: 6109452007

IRF1 Rabbit pAb

Anti-IRF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225638

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225638
Product Name:   Anti-IRF1 Rabbit pAb
Synonyms:   IRF1; Interferon regulatory factor 1; IRF-1
UNIPROT ID:   P10914
Background:    Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.
Immunogen:    A synthesized peptide derived from human IRF1
Applications:    WB,IHC-P,ICC/IF,IP,FC
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 37 kDa; Observed MW: 48 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded rat kidney using IRF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of IRF1 in Jurkat lysates using IRF1 antibody.

Immunofluorescence analysis of IRF1 in Hela using IRF1 antibody.
          Publications