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IRF4 Rabbit pAb

Anti-IRF4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216590

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216590
Product Name:   Anti-IRF4 Rabbit Polyclonal Antibody
Synonyms:   MUM1; LSIRF; SHEP8; NF-EM5
UNIPROT ID:   Q15306 (Gene Accession – BC015752 )
Background:    The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Immunogen:    Fusion protein of human IRF4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human brain tissue using 216590(IRF4 Antibody) at a dilution of 1/40(Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 216590(Anti-IRF4 Antibody) at a dilution of 1/40.
          Publications