Email: info@neweastbio.com   |  Call: 6109452007

IRF6 Rabbit pAb

Anti-IRF6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216591

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216591
Product Name:   Anti-IRF6 Rabbit Polyclonal Antibody
Synonyms:   LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
UNIPROT ID:   O14896 (Gene Accession – BC014852 )
Background:    This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human IRF6
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216591(IRF6 Antibody) at a dilution of 1/50(Nucleus and Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216591(Anti-IRF6 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 216591(Anti-IRF6 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D220876(Anti-IRF6 Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: 231 cells, mouse kidney tissue, Mouse lung tissue;
Primary antibody: 216591(IRF6 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes
          Publications