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IRGM Rabbit pAb

Anti-IRGM Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217546

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217546
Product Name:   Anti-IRGM Rabbit Polyclonal Antibody
Synonyms:   IFI1; IRGM1; LRG47; LRG-47
UNIPROT ID:   A1A4Y4 (Gene Accession – BC128168 )
Background:    This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn’s disease and tuberculosis.
Immunogen:    Fusion protein of human IRGM
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cardiovascular, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 217546(IRGM Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 217546(Anti-IRGM Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 217546(Anti-IRGM Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D222555(Anti-IRGM Antibody) at dilution 1/60.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Human hepatocellular carcinoma tissue;
Primary antibody: 217546(IRGM Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes
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