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IRS4 Rabbit pAb

Anti-IRS4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219872

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219872
Product Name:   Anti-IRS4 Rabbit Polyclonal Antibody
Synonyms:   IRS-4; PY160
UNIPROT ID:   O14654 (Gene Accession – NP_003595 )
Background:    IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.
Immunogen:    Synthetic peptide of human IRS4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219872(IRS4 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 219872(Anti-IRS4 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219872(Anti-IRS4 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D260524(Anti-IRS4 Antibody) at dilution 1/25.
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