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ITGA2B Rabbit pAb

Anti-ITGA2B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211299

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211299
Product Name:   Anti-ITGA2B Rabbit Polyclonal Antibody
Synonyms:   GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16
UNIPROT ID:   P08514 (Gene Accession – BC117443 )
Background:    ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen:    Fusion protein of human ITGA2B
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 211299(ITGA2B Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 211299(Anti-ITGA2B Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 211299(Anti-ITGA2B Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D122551(Anti-ITGA2B Antibody) at dilution 1/40.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human fetal liver tissue, Human placenta tissue;
Primary antibody: 211299(ITGA2B Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 minutes
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