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ITGAL Rabbit pAb

Anti-ITGAL Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S213642

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S213642
Product Name:   Anti-ITGAL Rabbit Polyclonal Antibody
Synonyms:   CD11A, LFA-1, LFA1A
UNIPROT ID:   P20701 (Gene Accession – NP_002200 )
Background:    ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human ITGAL
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 213642(ITGAL Antibody) at a dilution of 1/20(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 213642(Anti-ITGAL Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 213642(Anti-ITGAL Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D160572(Anti-ITGAL Antibody) at dilution 1/20.
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