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ITGB1 Rabbit pAb

Anti-ITGB1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216588

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216588
Product Name:   Anti-ITGB1 Rabbit Polyclonal Antibody
Synonyms:   CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
UNIPROT ID:   P05556 (Gene Accession – BC020057 )
Background:    Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Immunogen:    Fusion protein of human ITGB1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216588(ITGB1 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216588(Anti-ITGB1 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 216588(Anti-ITGB1 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D220869(Anti-ITGB1 Antibody) at dilution 1/50.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-7: Human stomach tissue, Human gastric carcinoma tissue, 823 cell, Human leiomyosarcoma tissue, A172 cell, HUVEC cell, Human gastric carcinoma and surrounding tissue lysates;
Primary antibody: 216588(ITGB1 Antibody) at dilution 1/100;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 5 seconds
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