Email: info@neweastbio.com   |  Call: 6109452007

ITM2C Rabbit pAb

Anti-ITM2C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219274

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219274
Product Name:   Anti-ITM2C Rabbit Polyclonal Antibody
Synonyms:   E25; BRI3; E25C; ITM3; BRICD2C
UNIPROT ID:   Q9NQX7 (Gene Accession – BC025742 )
Background:    Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Immunogen:    Fusion protein of human ITM2C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219274(ITM2C Antibody) at a dilution of 1/120(Lysosome).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 219274(Anti-ITM2C Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 219274(Anti-ITM2C Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D226178(Anti-ITM2C Antibody) at dilution 1/120.
          Publications