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IZUMO1R Rabbit pAb

Anti-IZUMO1R Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222045

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222045
Product Name:   Anti-IZUMO1R Rabbit Polyclonal Antibody
Synonyms:   JUNO; FOLR4; Folbp3
UNIPROT ID:   A6ND01 (Gene Accession – NP_001186135 )
Background:    Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane ‘fusogen’. Does not bind folate.
Immunogen:    Synthetic peptide of human IZUMO1R
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 222045(IZUMO1R Antibody) at a dilution of 1/40(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 222045(Anti-IZUMO1R Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 222045(Anti-IZUMO1R Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D263930(Anti-IZUMO1R Antibody) at dilution 1/40.
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