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JADE1 Rabbit pAb

Anti-JADE1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219490

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219490
Product Name:   Anti-JADE1 Rabbit Polyclonal Antibody
Synonyms:   PHF17
UNIPROT ID:   Q6IE81 (Gene Accession – BC032376 )
Background:    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.
Immunogen:    Fusion protein of human JADE1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 219490(JADE1 Antibody) at a dilution of 1/130(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 219490(Anti-JADE1 Antibody) at dilution 1/130.
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