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JAK3 Rabbit pAb

Anti-JAK3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221452

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221452
Product Name:   Anti-JAK3 Rabbit Polyclonal Antibody
Synonyms:   JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN
UNIPROT ID:   P52333 (Gene Accession – NP_000206 )
Background:    The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Immunogen:    Synthetic peptide of human JAK3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221452(JAK3 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221452(Anti-JAK3 Antibody) at dilution 1/25.
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