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JPT1 Rabbit pAb

Anti-JPT1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218975

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218975
Product Name:   Anti-JPT1 Rabbit Polyclonal Antibody
Synonyms:   HN1; ARM2; HN1A
UNIPROT ID:   Q9UK76 (Gene Accession – BC001420 )
Background:    Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 ‘Ser-33’ phosphorylation and degradation through the suppression of the inhibitory ‘Ser-9’ phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Immunogen:    Fusion protein of human JPT1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218975(JPT1 Antibody) at a dilution of 1/35(Nucleus and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218975(Anti-JPT1 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 218975(Anti-JPT1 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D225592(Anti-JPT1 Antibody) at dilution 1/35.
          Publications