Email: info@neweastbio.com   |  Call: 6109452007

KCNA1 Rabbit pAb

Anti-KCNA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219877

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219877
Product Name:   Anti-KCNA1 Rabbit Polyclonal Antibody
Synonyms:   EA1, MK1, AEMK, HBK1, HUK1, MBK1, RBK1, KV1.1
UNIPROT ID:   Q09470 (Gene Accession – NP_000208 )
Background:    This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Immunogen:    Synthetic peptide of human KCNA1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 15-50;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219877(KCNA1 Antibody) at a dilution of 1/30(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219877(Anti-KCNA1 Antibody) at dilution 1/30.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human brain malignant glioma tissue;
Primary antibody: 219877(KCNA1 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
          Publications