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KCNQ3 Rabbit pAb

Anti-KCNQ3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215248

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215248
Product Name:   Anti-KCNQ3 Rabbit Polyclonal Antibody
Synonyms:   EBN2; BFNC2; KV7.3
UNIPROT ID:   O43525 (Gene Accession – NP_004510 )
Background:    This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants.
Immunogen:    Synthetic peptide of human KCNQ3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 215248(KCNQ3 Antibody) at a dilution of 1/50(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 215248(Anti-KCNQ3 Antibody) at dilution 1/50.
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