NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261192 |
Product Name: Anti-Ki67 (10B6) Mouse Monoclonal Antibody |
Synonyms: MKI67; Antigen KI-67 |
UNIPROT ID: P46013 |
Background: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly(PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). |
Immunogen: Synthetic peptide corresponding to aa (CEDLAGFKELFQTPG) of human KI67, conjugated to KLH. |
Applications: IHC-P |
Recommended Dilutions: IHC: 1/50-1/100 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: 10B6-7D9-9H1 |
MW: – |
Isotype: IgG2b |
Purification: Ascitic Fluid |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Cell Biology |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human lymph node (A), esophagus (B), lung cancer (C), rectum cancer (D), using Ki67 (10B6) antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |