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KRT5 Rabbit pAb

Anti-KRT5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219699

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219699
Product Name:   Anti-KRT5 Rabbit Polyclonal Antibody
Synonyms:   CK5, K5, DDD, EBS2, KRT5A
UNIPROT ID:   P13647 (Gene Accession – BC071906 )
Background:    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Immunogen:    Synthetic peptide of human KRT5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219699(KRT5 Antibody) at a dilution of 1/25(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219699(Anti-KRT5 Antibody) at dilution 1/25.
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