NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261123 | ||||
Product Name: Anti-Ku80 (8H1) Mouse Monoclonal Antibody | ||||
Synonyms: XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr | ||||
UNIPROT ID: P13010 | ||||
Background: Ku80 the 80-kilodalton subunit of the Ku complex, also known as ATP-dependant DNA helicase II. A single stranded DNA-dependent ATP-dependent helicase. It functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. | ||||
Immunogen: Purified recombinant human Ku80 protein fragments expressed in E.coli | ||||
Applications: WB,ICC/IF,IP,ChIP | ||||
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 8H1-C3-G10 | ||||
MW: Calculated MW: 83 kDa; Observed MW: 86 kDa | ||||
Isotype: IgG1 | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human,Monkey | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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