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L3MBTL2 Rabbit pAb

Anti-L3MBTL2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219178

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219178
Product Name:   Anti-L3MBTL2 Rabbit Polyclonal Antibody
Synonyms:   L3MBT; H-l(3)mbt-l
UNIPROT ID:   Q969R5 (Gene Accession – BC017191 )
Background:    Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ‘Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ‘Lys-4’, ‘Lys-9’ or ‘Lys-27’.
Immunogen:    Fusion protein of human L3MBTL2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 219178(L3MBTL2 Antibody) at a dilution of 1/70(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 219178(Anti-L3MBTL2 Antibody) at dilution 1/70.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse thymus tissue lysate;
Primary antibody: 219178(L3MBTL2 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 35 seconds
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