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LAMA2 Rabbit pAb

Anti-LAMA2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222397

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222397
Product Name:   Anti-LAMA2 Rabbit Polyclonal Antibody
Synonyms:   LAMM; MDC1A
UNIPROT ID:   P24043 (Gene Accession – NP_000417 )
Background:    Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
Immunogen:    Synthetic peptide of human LAMA2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 222397(LAMA2 Antibody) at a dilution of 1/65(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 222397(Anti-LAMA2 Antibody) at dilution 1/65.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 222397(Anti-LAMA2 Antibody) at a dilution of 1/65.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D264544(Anti-LAMA2 Antibody) at dilution 1/65.
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