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Laminin alpha 5 Rabbit pAb

Anti-Laminin alpha 5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225453

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225453
Product Name:   Anti-Laminin alpha 5 Rabbit pAb
Synonyms:   Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
UNIPROT ID:   O15230
Background:    Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
Immunogen:    The antiserum was produced against synthesized peptide derived from human LAMA5. AA range:2381-2430
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 400 kDa; Observed MW: 400 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using LAMA5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of Laminin alpha 5 in RAW, HepG2, A549 lysates using Laminin alpha 5 antibody.
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