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LDOC1 Rabbit pAb

Anti-LDOC1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217571

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217571
Product Name:   Anti-LDOC1 Rabbit Polyclonal Antibody
Synonyms:   Mar7; BCUR1; Mart7
UNIPROT ID:   O95751 (Gene Accession – BC003104 )
Background:    The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Immunogen:    Fusion protein of human LDOC1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 217571(LDOC1 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 217571(Anti-LDOC1 Antibody) at dilution 1/50.
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