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LEF1 Rabbit mAb

Anti-LEF1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262465

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262465
Product Name:   Anti-LEF1 Rabbit Monoclonal Antibody
Synonyms:   LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
UNIPROT ID:   Q9UJU2
Background:    Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).
Immunogen:    A synthetic peptide of human LEF1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-3A4
MW:    Calculated MW: 44 kDa; Observed MW: 25-58 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of LEF1 in Jurkat lysates using LEF1 antibody.

Immunocytochemistry analysis of LEF1 (green) in Jurkat using LEF1 antibody,and DAPI(blue).
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