Email: info@neweastbio.com   |  Call: 6109452007

LEF1 Rabbit pAb

Anti-LEF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216614

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216614
Product Name:   Anti-LEF1 Rabbit Polyclonal Antibody
Synonyms:   LEF-1; TCF10; TCF7L3; TCF1ALPHA
UNIPROT ID:   Q9UJU2 (Gene Accession – BC050632 )
Background:    This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human LEF1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 216614(LEF1 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 216614(Anti-LEF1 Antibody) at dilution 1/50.
          Publications