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LEF1 Rabbit pAb

Anti-LEF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N226030

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N226030
Product Name:   Anti-LEF1 Rabbit pAb
Synonyms:   LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
UNIPROT ID:   Q9UJU2
Background:    Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).
Immunogen:    A synthetic peptide of human LEF1
Applications:    WB,IHC-F,IHC-P,ICC/IF,FC,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 44 kDa; Observed MW: 25-58 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of LEF1 in Jurkat lysates using LEF1 antibody

Immunocytochemistry analysis of LEF1 (green) in Jurkat using LEF1 antibody,and DAPI(blue).

Western blot analysis of LEF1 in C6 lysates using LEF1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using LEF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications