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LEFTY2 Rabbit pAb

Anti-LEFTY2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217891

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217891
Product Name:   Anti-LEFTY2 Rabbit Polyclonal Antibody
Synonyms:   EBAF; LEFTA; TGFB4; LEFTYA
UNIPROT ID:   O00292 (Gene Accession – BC035718 )
Background:    This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.
Immunogen:    Full length fusion protein
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: Oct-50;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217891(LEFTY2 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217891(Anti-LEFTY2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 217891(Anti-LEFTY2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D223312(Anti-LEFTY2 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal muscle tissue;
Primary antibody: 217891(LEFTY2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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