Email: info@neweastbio.com   |  Call: 6109452007

LGR5 Rabbit pAb

Anti-LGR5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216615

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216615
Product Name:   Anti-LGR5 Rabbit Polyclonal Antibody
Synonyms:   FEX; HG38; GPR49; GPR67; GRP49
UNIPROT ID:   O75473 (Gene Accession – BC096324 )
Background:    The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human LGR5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 216615(LGR5 Antibody) at a dilution of 1/80(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 216615(Anti-LGR5 Antibody) at dilution 1/80.
          Publications