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LIG1 Rabbit pAb

Anti-LIG1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217367

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217367
Product Name:   Anti-LIG1 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P18858 (Gene Accession – BC110622 )
Background:    This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human LIG1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217367(LIG1 Antibody) at a dilution of 1/70(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217367(Anti-LIG1 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 217367(Anti-LIG1 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D222243(Anti-LIG1 Antibody) at dilution 1/70.
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